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Linzolid 400 mg Tablet is a brand-name antibiotic produced by Incepta Pharmaceuticals in Bangladesh. Its active ingredient, linezolid, belongs to the oxazolidinone class and is used to treat various serious bacterial infections, especially those resistant to other antibiotics.
🔹 Uses of Linzolid 400 mg
Linezolid is effective against infections caused by Gram-positive bacteria, including:
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Methicillin-resistant Staphylococcus aureus (MRSA)
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Vancomycin-resistant Enterococcus faecium (VRE)
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Streptococcus pneumoniae
Common indications include:
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Community-acquired and nosocomial pneumonia
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Complicated and uncomplicated skin and soft tissue infections
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Infections caused by multidrug-resistant Gram-positive bacteri
In adults, the typical dosage for uncomplicated skin infections is 400 mg orally every 12 hours for 10 to 14 days
⚠️ Side Effects
Common side effects of linezolid include
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Headache
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Nausea and vomiting
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Diarrhea
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Dizziness
Serious side effects may occur, especially with prolonged use (beyond 28 days), and can include
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Bone marrow suppression (e.g., thrombocytopenia, anemia)
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Peripheral and optic neuropathy
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Lactic acidosis
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Serotonin syndrome, particularly when combined with serotonergic drugs
Regular monitoring of blood counts and neurological status is recommended during therapy.
⚠️ Important Precautions
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Avoid tyramine-rich foods (e.g., aged cheeses, cured meats) to reduce the risk of hypertensive reactions.
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Do not use concurrently with monoamine oxidase inhibitors (MAOIs) or serotonergic drugs without medical supervision.
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Use with caution in patients with uncontrolled hypertension, thyroid disorders, or seizure history .
💊 Storage Instructions
Store Linzolid tablets at room temperature (20°C to 25°C), away from heat, moisture, and direct light.
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